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Clinical Applications

PuraStat is intended for hemostasis of mild and moderate bleeding post ESD or EMR, as an adjunct, bridge, prophylactic or rescue therapy for intraprocedural venous bleeding or prophylactic therapy to prevent post procedure bleeding in Gastrointestinal (GI) bleeding.

PuraStat is also indicated for the symptomatic management of Rectal Mucositis (RM), such as radiation proctitis that may be caused by chemotherapy or radiotherapy. Click tabs below for examples.

Resection
ERCP

See how these examples demonstrate the application of PuraStat during resection procedures, such as ESD, EMR, and polypectomy.

Hemostasis with PuraStat ^® During ESD/EMR Procedure

Fig. 1: Barrett’s intramucosal cancer

Fig. 2: Bleeding during ESD. Yellow arrow indicates bleeding point; White dot circle indicates resected area

Fig. 3: White dot circle: transparent PuraStat covered the bleeding site: Yellow arrow: bleeding point; Blue arrow: tip of the catheter

Fig. 4: Hemostasis achieved

Source 1–4: Professor Pradeep Bhandari, Queen Alexandra Hospital, United Kingdom

Resection of a Large Circumferential, Recto-sigmoid Polyp

Fig. 1: Carpet adenoma of rectum

Fig. 2: Snare resection of the lesion

Fig. 3: White dot circle: transparent PuraStat covered the bleeding site; Yellow arrow: bleeding point

Fig. 4: Hemostasis was achieved

Source 1–4: Professor Pradeep Bhandari, Queen Alexandra Hospital, United Kingdom

Using PuraStat to Manage Bleeding in Endoscopic Resection (Professor Bhandari)

Using PuraStat during Cecal Polyp Resection (Professor Neumann)

See related case studies:

Hemostasis with PuraStat ^® During ESD/EMR Procedure (Professor Bhandari)

Experience of PuraStat ^® During Resection of a Large Circumferential, Recto-sigmoid Polyp (Professor Bhandari)

See how these examples demonstrate the application of PuraStat during procedures in conjunction with ERCP.

Hemostasis with PuraStat ^® in Papillectomy

Fig.1: Adenoma of the duodenal major papilla

Fig. 2: Unremarkable resection site after endoscopic papillectomy

Fig. 3: Severe arterial bleeding on the following day

Fig. 4: Persistent bleeding despite of injection of adrenaline (1:10000)

Fig. 5: Transparent PuraStat covered the bleeding site. Complete hemostasis was achieved after 45 seconds

Fig. 6 : Clear bleeding site two days later. Endoprotheses (pancreatic and bile duct) could be removed

Source 1-2: Professor Jens Tischendorf, Rhein-Maas Hospital, Würselen, Germany

Hemostasis with PuraStat ^® after Endoscopic Sphincterotomy

Fig.1 Confirmation of bleeding from Sphincterotomy site

Fig.2 Filling the catheter with PuraStat

Fig.3 Application of PuraStat

Fig. 4 Confirmation of hemostasis

Source 1–4: Dr. Ken Ogura, Osaka Medical and Pharmaceutical University Hospital, Japan

Using PuraStat after Endoscopic Sphincterotomy (Dr. Ken Ogura)

See related case studies:

Hemostasis with PuraStat in Papillectomy (Professor Tischendorf)

Practical Application of Hemostatic Techniques Using PuraStat ^® for Bleeding After Endoscopic Sphincterotomy (Dr. Ogura)

Pura Stat Ordering Information

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