Clinical Studies

de Nucci, G., Reati, R., Arena, I., Bezzio, C., Devani, M., Corte, C., Morganti, D., Mandelli, E., Omazzi, B., Redaelli, D., Saibeni, S., Dinelli, M. and Manes, G., 2020. Efficacy of a novel self-assembling peptide hemostatic gel as rescue therapy for refractory acute gastrointestinal bleeding. Endoscopy. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1145-3412
Ortenzi, M. and Haji, A., 2020. Safety and feasibility of PuraStat® in laparoscopic colorectal surgery (Feasibility study). Minimally Invasive Therapy & Allied Technologies, pp.1-6. https://www.tandfonline.com/doi/abs/10.1080/13645706.2020.1739711?journalCode=imit20
Subramaniam, S., Kandiah, K., Thayalasekaran, S., Longcroft-Wheaton, G. and Bhandari, P., 2019. Haemostasis and prevention of bleeding related to ER: The role of a novel self-assembling peptide. United European Gastroenterology Journal, 7(1), pp.155-162. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374844/

Pioche, M., Camus, M., Rivory, J., Leblanc, S., Lienhart, I., Barret, M., Chaussade, S., Saurin, J., Prat, F. and Ponchon, T., 2016. A self-assembling matrix-forming gel can be easily and safely applied to prevent delayed bleeding after endoscopic resections. Endoscopy International Open, 04(04), pp.E415-E419. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831935/
Subramaniam, S., Kandiah, K., Fujimoto, A., Yahagi, N., Uraoka, T. and Bhandari, P., 2017. Minimising the risk of delayed bleeding in colonic endoscopic submucosal dissection: Is there a role for a novel haemostatic peptide?. United European Gastroenterology Journal, 5, pp.A1-A160. https://journals.sagepub.com/doi/full/10.1177/2050640617725668
Subramaniam, S., Kandiah, K., Thayalasekaran, S., Longcroft-Wheaton, G. and Bhandari, P., 2018. Bleeding during Endoscopic Submucosal Dissection: A Randomised Controlled Trial of a Novel Haemostatic Agent. United European Gastroenterology Journal, 6. https://journals.sagepub.com/doi/pdf/10.1177/2050640618792817

Giritharan, S., Salhiyyah, K., Tsang, G. and Ohri, S., 2018. Feasibility of a novel, synthetic, self-assembling peptide for suture-line haemostasis in cardiac surgery. Journal of Cardiothoracic Surgery, 13(1). https://pubmed.ncbi.nlm.nih.gov/29903028/
Masuhara, H., Fujii, T., Watanabe, Y., Koyama, N. and Tokuhiro, K., 2012. Novel Infectious Agent-Free Hemostatic Material (TDM-621) in Cardiovascular Surgery. Annals of Thoracic and Cardiovascular Surgery, 18(5), pp.444-451. https://pubmed.ncbi.nlm.nih.gov/22986759/
Morshuis, M., Schönbrodt, M. and Gummert, J., 2019. Safety and Performance of a Self-Assembling Peptide Haemostat for the Management of Bleeding after Left Ventricular Assist Device Implantation: Outcomes of a Post Market Clinical Follow-Up Study. The Journal of Heart and Lung Transplantation, 38(4), p.S194. https://www.sciencedirect.com/science/article/pii/S1053249819304711

Lee, M., Ma, Z. and Ananda, A., 2017. A novel haemostatic agent based on self-assembling peptides in the setting of nasal endoscopic surgery, a case series. International Journal of Surgery Case Reports, 41, pp.461-464. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709301/

White K. and Henson, C. 2019. PWE-048 Endoscopically-delivered PuraStat for the treatment of severe haemorrhagic radiation proctopathy: A case series. Gut, 68, A195-A196. https://gut.bmj.com/content/68/Suppl_2/A195.2
White K, Henson C. 2021. Endoscopically delivered Purastat for the treatment of severe haemorrhagic radiation proctopathy: a service evaluation of a new endoscopic treatment for a challenging condition, Frontline Gastroenterology https://fg.bmj.com/content/early/2021/01/18/flgastro-2020-101735