GI endoscopy
3-D Matrix is committed to advancing patients outcomes in gastroenterology and supporting healthcare professionals through its innovative self-assembling peptide technology.
Our flagship product in gastroenterology, PuraStat, is a ready-to-use, slightly viscous hydrogel, composed of self-assembling peptides (SAPs).
Founded at the Massachusetts Institute of Technology (MIT), PuraStat is licenced as a medical device to achieve haemostasis and minimise delayed bleeding. There is literature that suggests
PuraStat facilitates the re-epithelization of the mucosal layer, promoting healing (1-2).
Focus Areas & Procedures Overview
Focus Areas & Procedures
Focus Areas & Procedures
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PuraStat is also indicated for the reduction of delayed bleeding following gastrointestinal endoscopic submucosal dissection (ESD) procedures in the colon(3).
1.Uraoka, T., Ochiai, Y., Fujimoto, A., et al. (2016) ‘A novel fully synthetic and self-assembled peptide solution for endoscopic submucosal dissection-induced ulcer in the stomach.’ Gastrointest Endosc. 83(6):1259-64. doi: 10.1016/j.gie.2015.11.015. Epub 2015 Dec 1. PMID: 26608126
2. Zulli, C., Gagliardi, M., Fusco, M., Abbatiello, C., Sica, M., Maurano, A. (2023) ‘Off-label use of novel hemostatic gel to treat wound dehiscence after stapled hemorrhoidectomy. Endoscopy’ 55(S 01):E557-E558. doi: 10.1055/a-2045-7426. Epub 2023 Mar 17. PMID: 36931308; PMCID: PMC10023250.
3.PuraStat IFU-007 Rev 2
